Mucin: what makes tears stick to the eye

Part 03 · 01
01

The cell surface naturally repels water

Without mucin, tears struggle to cling on.

02

Two kinds of mucin work together

The surface glycocalyx, plus gel mucin from goblet cells.

03

The surface becomes ‘water-loving’

So tears can spread evenly and stay longer.

Inflammation strips away the foundation

Part 03 · 02
01

Fewer goblet cells

Chronic inflammation reduces goblet cell numbers.

02

A damaged glycocalyx

The surface loses its water-loving coating.

03

Tears bead up and slide off

Like water on a freshly waxed car: the film breaks faster.

From an ‘oil’ problem to a ‘stick’ problem

Part 03 · 03
Long-term meibomian gland dysfunction (MGD)
↓
Unstable tear film, raised tear osmolarity
↓
Chronic surface inflammation
↓
Goblet cell and mucin damage
↓
Tears can't adhere: mucin deficiency

Inflammation damages the glands too. Chronic inflammation further degrades the oil, creating a vicious cycle (part 4).

Key takeaways

Part 03
  1. 01Mucin turns a water-repelling surface into a water-loving one
  2. 02Inflammation reduces goblet cells and damages the glycocalyx
  3. 03Long-standing oil problems can erode the eye's ability to hold tears
Dry eye / Mt Hawthorn

Book an eye surface assessment.

Eyes that often feel dry or gritty, or vision that comes and goes? Find out which type you have and what’s driving it.

Book

General health information only, not personal advice. Everyone’s eyes are different. An optometrist or doctor should examine you before any treatment is decided.

WA Eye Care · Room 3, 103 Scarborough Beach Road, Mt Hawthorn WA 601608 6288 4218 · info@waeyecare.com.au