Where are the meibomian glands?

Part 02 · 01
01

Inside the tarsal plate of each eyelid

Around 25–40 in the upper lid and 20–30 in the lower.

02

Openings sit on the lid margin, behind the lashes

A row of tiny openings, hard to see with the naked eye.

03

Blinking squeezes the oil out

The lid muscles push oil onto the tear film with each blink.

How is the oil made?

Part 02 · 02
01

Holocrine secretion

Cells fill with lipid, then break down entirely into oil.

02

Mostly lipids

Mainly wax and cholesterol esters, plus some polar lipids.

03

Healthy meibum is clear and fluid

It melts at eyelid temperature and spreads with each blink.

A good oil layer does three jobs

Part 02 · 03

Slows evaporation

It sits over the watery layer like a lid, reducing water loss.

Keeps the tear film smooth and stable

The film lasts longer after each blink, for clearer, steadier vision.

Seals the lid margin

It stops tears spilling over, and helps seal the lids when they close.

When the glands get ‘blocked’: MGD

Part 02 · 04
01

Blocked, keratinised openings

Oil can't get out, so it builds up and thickens.

02

Oil turns thick and cloudy

From ‘olive oil’ to ‘toothpaste’: it no longer spreads.

03

Long-term blockage leads to atrophy

Glands shorten or disappear, and rarely grow back.

How the tear film fails

Part 02 · 05
Fig. 06 — Tear film and oil glands01 / 05
Dry spot EyelidOil gland OilWaterEye surface 0.0 s Warmth
Step 01 / Healthy

Tear film drawn thousands of times thicker than real. Not to scale.

What poor oil does to the tear film

Part 02 · 06
01

A thin, patchy oil layer

Tears evaporate faster and the film breaks up early.

02

Tears turn ‘salty’

Raised osmolarity irritates and inflames the surface.

03

Surface damage

Dryness, burning, grittiness, and vision that comes and goes.

Signs your oil may be the problem

Part 02 · 07

Dry, burning, gritty eyes

Often worse in the evening, after screen time, or in air-con.

Vision that comes and goes

It clears after a few blinks, then blurs again.

Watery eyes, surprisingly

An irritated surface triggers reflex tearing: dry eyes that water.

Sticky lids, red lid margins

Lid margins may look red or thickened, or have discharge.

Key takeaways

Part 02
  1. 01Meibomian glands sit inside the lids and make the tear film's oil
  2. 02Thick oil and blocked openings mean MGD
  3. 03Poor oil → faster evaporation → saltier tears → inflammation
Dry eye / Mt Hawthorn

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General health information only, not personal advice. Everyone’s eyes are different. An optometrist or doctor should examine you before any treatment is decided.

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